This is a dope story about how lab animals may make bad research subjects. Basically, their confined existences may drive them bonkers, as in the case of lab mice who do backflips once every second for up to half an hour. Does their bizarro mental status cast aspersions on the data gleaned from research on them?
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- If they develop abnormal behaviors, it might mean they are abnormal test subjects... My first concern was that the more these people examined complex brain function, the more it really started to matter whether these animals were normal or not. [Hanno Wurbel, animal behaviorist]
- If you grow up with evolutionary thinking or behavioral ecology—and this is now a more common thing—that's a scene where you think differently about housing conditions. You don't see animals as little machines that will always behave the same way if you put them in the same environment. You look at individuals differently, and you ask, 'What are we doing if we ignore the evolutionary history of a species and just keep them in a clean cage with nothing else?' [Barbara Konig, zoologist]
- What we're interested in is a model that has higher predictive power of whether a therapeutic regime works for humans," Hockly says. "Humans have a very complex environment. If the mice are sitting around twiddling their thumbs like they're in prison, you probably don't have a good model. [Emma Hockly, behavioral pharmacologist]
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